A leading manufacturer and supplier of herbal
extracts in China Organic Herb Inc.
Address: NO.2405,Dushidongjia.Xiongju,Mawangdui
Road,Changsha£¬China Phone:+86 731 2967872
Mobile: +86-135-17475149
Fax:+86-731-2967861 Attn: Ms.lily liu
E-mail:Email:lily@organic-herb.com
www.organic-herb.com
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Broccoli Extract
Broccoli Extract Brassica oleracea Botrytis
cymosa Sulforaphane indole-3-carbinol
Broccoli Extract
Brassica oleracea Botrytis cymosa Sulforaphane indole-3-carbinol
Indole-3-carbinol (I3C)
is a secondary metabolite found in cruciferous vegetables such as
broccoli, cauliflower, kale, cabbage and brussels sprouts. A secondary
metabolite is one not found preformed in vegetables, but formed after an
enzyme in the vegetable (myrosinase) is exposed to a phytochemcial in
the vegetable (glucobrassicin). This can occur only when vegetable cells
are crushed or eaten, and is referred to as enzymatic hydrolysis.
I3C, thus formed, is
then broken down in the presence of acid (as in the acid environment of
the stomach) to various by-products such as diindolylmethane (DIM),
which are then absorbed.
Why is this important? Because I3C has been shown to inhibit cancer
cells in animal cancer models of the mammary, liver, and lung.5-7 It is
currently being evaluated in human clinical trials as a potential
chemopreventive agent against breast and ovarian cancers.8
I3C appears to work by
upregulating or modulating certain enzymes that improve the
detoxification of various potential carcinogens¢®¨£although it appears
to be the breakdown products that have this effect rather than IC3
itself. Furthermore, it is not clear that DIM is the only breakdown
product of importance.9
Certainly DIM by itself has an effect, but these other products may also
be important for the overall cancer-inhibiting action. As most of the
research to date has focused on I3C, it seems prudent at this time to
use supplements containing I3C instead of DIM. Just make sure you take
it with meals and have sufficient acidifying capacity in your stomach.
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Sales Manager:lily liu
Bring nature to better
life! Organic Herb Inc.
Address:N0.2405,Dushidongjia.Xiongju,Mawangdui North Road,Furong
District,changsha,China Phone: +86 731
2967872(NEW) Fax: +86 731 2967861(NEW)
Mobile: +86 135 17475149
Email: E-mail:lily@organic-herb.com MSN
messenger£º E-mail:lily@organic-herb.com
Website: www.organic-herb.com |